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規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
10 mg	In-stock	￥566.00	登錄后可見(jiàn)	- +
20 mg	In-stock	￥948.00	登錄后可見(jiàn)	- +

規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

10 mg

In-stock

￥566.00

登錄后可見(jiàn)

- +

20 mg

In-stock

￥948.00

登錄后可見(jiàn)

- +

基本信息

英文名稱	Triptolide (PG490)
中文名稱	雷公藤甲素；雷藤素甲；雷公藤內(nèi)酯醇；雷公藤多甙
CAS號(hào)	38748-32-2
分子式	C20H24O6
分子量	360.40
MDL	MFCD00210565
外觀	white solid powder
儲(chǔ)存條件	4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

安全信息

產(chǎn)品詳情

Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It functions as a NF-κB inhibitor with dual actions by disruption of p65/CBP interaction and by reduction of p65 protein. Triptolide (PG490) abrogates the transactivation function of heat shock transcription factor 1 (HSF1). Triptolide inhibits MDM2 and induces apoptosis through a p53-independent pathway.

相關(guān)文獻(xiàn)

Natural product triptolide induces GSDME-mediated pyroptosis in head and neck cancer through suppressing mitochondrial hexokinase-ΙΙ.

PMID: 34108030 PMCID: PMC8188724 DOI: 10.1186/s13046-021-01995-7

PMID: 27999372 PMCID: PMC5187939 DOI: 10.3390/ijms17122139

PMID: 26134275 PMCID: PMC4488747 DOI: 10.1038/srep11747

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雷公藤甲素；雷藤素甲；雷公藤內(nèi)酯醇；雷公藤多甙

38748-32-2 98+% In-stock