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依氟鳥(niǎo)氨酸鹽酸鹽一水合物

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Eflornithine Hydrochloride Monohydrate

產(chǎn)品編號(hào):CL1653 CAS No.:96020-91-6 MDLNo: 分子式:C6H15ClF2N2O3 分子量:236.64
規(guī)格 庫(kù)存 目錄價(jià) 會(huì)員專(zhuān)享價(jià) 數(shù)量
500 mg In-stock ¥388.00 登錄后可見(jiàn)
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1 g In-stock ¥588.00 登錄后可見(jiàn)
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5 g In-stock ¥1288.00 登錄后可見(jiàn)
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基本信息
英文名稱(chēng) Eflornithine Hydrochloride Monohydrate
中文名稱(chēng)依氟鳥(niǎo)氨酸鹽酸鹽一水合物
CAS號(hào)96020-91-6
分子式C6H15ClF2N2O3
分子量236.64
外觀(guān)White to off-white powder
儲(chǔ)存條件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
產(chǎn)品詳情

Eflornithine, also known as Difluoromethylornithine, is a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. This agent has been shown to induce apoptosis in leiomyoma cells.

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